Genetics of 35 blood and urine biomarkers in the UK Biobank.

doi:10.1038/s41588-020-00757-z

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Article

Genetics of 35 blood and urine biomarkers in the UK Biobank.

Nature genetics - 1 Feb 2021

Sinnott-Armstrong Nasa, Tanigawa Yosuke, Amar David, Mars Nina, Benner Christian, Aguirre Matthew, Venkataraman Guhan Ram, Wainberg Michael, Ollila Hanna M, Kiiskinen Tuomo, Havulinna Aki S, Pirruccello James P, Qian Junyang, Shcherbina Anna, Rodriguez Fatima, Assimes Themistocles L, Agarwala Vineeta, Tibshirani Robert, Hastie Trevor, Ripatti Samuli, Pritchard Jonathan K, Daly Mark J, Rivas Manuel A

Abstract excerpt

Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 individuals). We identify 1,857 loci associated with at least one trait, containing 3,374 fine-mapped associations and additional sets of large-effect (>0.1 s.d.) protein-altering, human leukocyte antigen (HLA) and copy number...

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PMID: 33462484
DOI: 10.1038/s41588-020-00757-z
PMCID: PMC7867639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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