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Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

13 Jan 2021

Abstract excerpt

BACKGROUND: Clinical laboratory (lab) tests are used in clinical practice to diagnose, treat, and monitor disease conditions. Test results are stored in electronic health records (EHRs), and a growing number of EHRs are linked to patient DNA, offering unprecedented opportunities to query relationships between genetic risk for complex disease and quantitative physiological measurements collected on large...

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PMID: 33441150
DOI: 10.1186/s13073-020-00820-8

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