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Cardiovascular-kidney-metabolic health, genetic susceptibility, and incident cancer risk: a prospective UK biobank cohort and machine learning study.

Frontiers in endocrinology - 1 Jan 2026

He Xue, An Junqiao, Yan Chunjia, Zhou Yutong, Wu Ziyan, Xu Mengyao, He Qingyong

Abstract excerpt

Background: It remains unclear whether cardiovascular-kidney-metabolic (CKM) syndrome and genetic susceptibility are associated with cancer incidence. This study aims to evaluate the associations between CKM health status, genetic susceptibility, and cancer incidence, and to develop a machine learning-based prediction model for cancer risk in patients with advanced CKM syndrome. Methods: This study included...

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Identifiers

PMID: 42609333
DOI: 10.3389/fendo.2026.1884752
PMCID: PMC13477978

Genes

CKM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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