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Article

Non human primate models for Alzheimer’s disease-related research and drug discovery

19 Dec 2016

Abstract excerpt

INTRODUCTION: Pathophysiological mechanisms underlying Alzheimer's disease (AD) remain insufficiently documented for the identification of accurate diagnostic markers and purposeful target discovery and development. Nonhuman primates (NHPs) have important translational value given their close phylogenetic relationship to humans and similar developmental paths in (neuro)anatomy, physiology, genetics, and neural...

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PMID: 27960560
DOI: 10.1080/17460441.2017.1271320

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