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Article

Reimagining dots and dashes: Visualizing structure and function of organelles for high-content imaging analysis.

Cell chemical biology - 18 Mar 2021

Chin Marcus Y, Espinosa Jether Amos, Pohan Grace, Markossian Sarine, Arkin Michelle R

Abstract excerpt

Organelles are responsible for biochemical and cellular processes that sustain life and their dysfunction causes diseases from cancer to neurodegeneration. While researchers are continuing to appreciate new roles of organelles in disease, the rapid development of specifically targeted fluorescent probes that report on the structure and function of organelles will be critical to accelerate drug discovery. Here, we...

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Identifiers

PMID: 33600764
DOI: 10.1016/j.chembiol.2021.01.016
PMCID: PMC7995685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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