Article

Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe

2022-02-15

Abstract excerpt

Lysosomes are multifunctional organelles involved in macromolecule degradation, nutrient sensing and autophagy. Live imaging has revealed lysosome subpopulations with dynamics and characteristic cellular localization. An as-yet unanswered question is whether lysosomes are spatially organized to coordinate and integrate their functions. Combined with super-resolution microscopy, we designed a small organic fluoresc...

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Literature Corpus work: 2f4abcbc-0076-5412-955b-ad0ce771583a
DOI: 10.1101/2022.02.14.480395

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