Article

DUX4 regulates oocyte to embryo transition in human

2019-08-12

Abstract excerpt

In oocyte to embryo transition, the fertilized oocyte undergoes final maturation and the embryo genome is gradually activated during the first three cell divisions. How this transition is coordinated and which factors drive the processes in humans is largely unknown. Here we studied the role of the double homeodomain transcription factor DUX4 in regulating the human oocyte to embryo transition. DUX4 knockdown zygo...

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Literature Corpus work: d7d4bb20-f319-5263-9891-d3299b891451
DOI: 10.1101/732289

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