Article

Male sex hormone and reduced plakoglobin jointly impair atrial conduction and cardiac sodium currents

2022-06-04

Abstract excerpt

Androgenic anabolic steroids (AAS) are commonly abused by young men. Male sex associates with earlier manifestation of common and rare cardiac conditions including atrial fibrillation and arrhythmogenic right ventricular cardiomyopathy (ARVC). Clinical data suggest an atrial involvement in ARVC. The disease is caused by desmosomal gene defects such as reduced plakoglobin expression. Analysis of clinical records fr...

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Literature Corpus work: d7c37d9a-80b9-557b-bd51-560f4e5ebe29
DOI: 10.1101/2022.06.03.494748

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