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Article

Matters of the heart: Cellular sex differences.

Journal of molecular and cellular cardiology - 1 Nov 2021

Walker Cierra J, Schroeder Megan E, Aguado Brian A, Anseth Kristi S, Leinwand Leslie A

Abstract excerpt

Nearly all cardiovascular diseases show sexual dimorphisms in prevalence, presentation, and outcomes. Until recently, most clinical trials were carried out in males, and many animal studies either failed to identify the sex of the animals or combined data obtained from males and females. Cellular sex in the heart is relatively understudied and many studies fail to report the sex of the cells used for in vitro...

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Identifiers

PMID: 34166708
DOI: 10.1016/j.yjmcc.2021.04.010
PMCID: PMC8571046

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