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Article

Sex differences in pulmonary (arterial) hypertension: does it matter?

23 Jul 2025

Abstract excerpt

PURPOSE OF REVIEW: This review synthesizes the current prevailing theories behind the 'sex paradox' or 'sex puzzle' in pulmonary arterial hypertension (PAH), a disease marked by sexual dimorphism. To a lesser extent, we also review sex differences in other forms of pulmonary hypertension. RECENT FINDINGS: Although more females than males develop PAH worldwide, female sex is associated with improved right...

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PMID: 40767089
DOI: 10.1097/mcp.0000000000001197

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