Article

Mutations in <i>RPL3L</i> and <i>MYZAP</i> increase risk of atrial fibrillation

2017-11-21

Abstract excerpt

We performed a meta-analysis of genome-wide association studies on atrial fibrillation (AF) among 14,710 cases and 373,897 controls from Iceland and 14,792 cases and 393,863 controls from the UK Biobank, focusing on low frequency coding and splice mutations, with follow-up in samples from Norway and the US. We observed associations with two missense (OR=1.19 for both) and one splice-donor mutation (OR=1.52) in RP...

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Literature Corpus work: d7ae8c6b-c333-5938-84a7-1b41bfffa62f
DOI: 10.1101/223578

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