Article

Chromatin topology control by a muscle-specific ribosomal protein

2026-06-26

Abstract excerpt

<h4>SUMMARY</h4> Three-dimensional genome organization stabilizes cell-type-specific gene expression, yet the tissue-restricted factors that maintain chromatin insulation remain poorly understood. Here, we identify the muscle-specific ribosomal protein Rpl3l as an unexpected nuclear regulator of genome architecture in atrial cardiomyocytes. Rpl3l is enriched in the nucleus and nucleolus, where it binds its own ge...

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Literature Corpus work: bc647f4d-387b-52da-81f1-ba93a43768db
DOI: 10.64898/2026.06.23.733628

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