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Article

A frameshift deletion in the sarcomere gene MYL4 causes early-onset familial atrial fibrillation

14 Oct 2016

Abstract excerpt

AIMS: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in man, causing substantial morbidity and mortality with a major worldwide public health impact. It is increasingly recognized as a highly heritable condition. This study aimed to determine genetic risk factors for early-onset AF. METHODS AND RESULTS: We sequenced the whole genomes of 8453 Icelanders and imputed genotypes of the 25.5...

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Share to Atrial Fibrillation Management and Outcomes
Share to Cardiac electrophysiology and arrhythmias
Share to Genomics and Rare Diseases

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PMID: 27742809
DOI: 10.1093/eurheartj/ehw379

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