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Article

Noninvasive Detection of BCL2, BCL6, and MYC Translocations in Diffuse Large B-Cell Lymphoma

2016-12-02

Abstract excerpt

Abstract Background: Diffuse large B cell lymphoma (DLBCL) is a clinically heterogeneous disease, where almost half of patients fail to fully respond to therapy and have poor outcomes. Prognostic molecular markers, including translocations in BCL2, BCL6, and MYC, can help identify patients at high risk for treatment failure. However, these markers rely on diagnostic tumor samples which must be obtained invasively...

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Literature Corpus work
d78b1af6-e53a-5ab5-ae8f-ac957ab26aa9
DOI
10.1182/blood.v128.22.2930.2930
Open publication

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