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Article

Diffuse large B-cell lymphoma genotyping on the liquid biopsy.

Blood - 6 Apr 2017

Rossi Davide, Diop Fary, Spaccarotella Elisa, Monti Sara, Zanni Manuela, Rasi Silvia, Deambrogi Clara, Spina Valeria, Bruscaggin Alessio, Favini Chiara, Serra Roberto, Ramponi Antonio, Boldorini Renzo, Foà Robin, Gaidano Gianluca

Abstract excerpt

Accessible and real-time genotyping for diagnostic, prognostic, or treatment purposes is increasingly impelling in diffuse large B-cell lymphoma (DLBCL). Cell-free DNA (cfDNA) is shed into the blood by tumor cells undergoing apoptosis and can be used as source of tumor DNA for the identification of DLBCL mutations, clonal evolution, and genetic mechanisms of resistance. In this study, we aimed at tracking the...

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Identifiers

PMID: 28096087
DOI: 10.1182/blood-2016-05-719641

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