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Circulating Tumor DNA Reflects Histologic and Clinical Characteristics of Various Lymphoma Subtypes.

Cancer research and treatment - 1 Jan 2024

Kim Jin Ju, Kim Hye Min, Kim Hongkyung, Kim Soo-Jeong, Lee Seung-Tae, Choi Jong Rak, Shin Saeam, Hwang Doh Yu

Abstract excerpt

PURPOSE: We designed and evaluated the clinical performance of a plasma circulating tumor DNA (ctDNA) panel of 112 genes in various subtypes of lymphoma. MATERIALS AND METHODS: Targeted deep sequencing with an error-corrected algorithm was performed in ctDNA from plasma samples that were collected before treatment in 42 lymphoma patients. Blood buffy coat was utilized as a germline control. We evaluated the...

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Biomarkers, Tumor
Circulating Tumor DNA
High-Throughput Nucleotide Sequencing
Liquid Biopsy
Lymphoma

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PMID: 37475138
DOI: 10.4143/crt.2023.667
PMCID: PMC10789961

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