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Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay

12 Jun 2018

Abstract excerpt

We sought to define the genomic landscape of diffuse large B-cell lymphoma (DLBCL) by using formalin-fixed paraffin-embedded (FFPE) biopsy specimens. We used targeted sequencing of genes altered in hematologic malignancies, including DNA coding sequence for 405 genes, noncoding sequence for 31 genes, and RNA coding sequence for 265 genes (FoundationOne-Heme). Short variants, rearrangements, and copy number...

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PMID: 29895903
DOI: 10.1038/s41408-018-0089-0

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