Article

Chemoproteomics yields a selective molecular host for acetyl-CoA

2022-12-19

Abstract excerpt

Chemoproteomic profiling is a powerful approach to define the selectivity of small molecules and endogenous metabolites with the human proteome. In addition to mechanistic studies, proteome specificity profiling also has the potential to identify new scaffolds for biomolecular sensing. Here we report a chemoproteomics-inspired strategy for selective sensing of acetyl-CoA. First, we use chemoproteomic capture exper...

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Literature Corpus work: d774beb8-5ce5-5ae3-a0c5-c75b781901ba
DOI: 10.1101/2022.12.19.521087

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