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Dexmedetomidine Alleviates Inflammatory Response and Oxidative Stress Injury of Vascular Smooth Muscle Cell via α2AR/PI3K/AKT Pathway in Intracranial Aneurysm

2022-02-25

Abstract excerpt

Vascular smooth muscle cell (VSMC) phenotypic modulation regulates the initiation and progression of intracranial aneurysm (IA). Dexmedetomidine (DEX) is reported to play neuroprotective roles in patients with craniocerebral injury. Therefore, we investigate the biological functions of DEX and its mechanisms against IA formation and progression. Rat primary VSMCs were isolated from Sprague-Dawley rats. IA and STA...

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Literature Corpus work: d764aa94-e95f-569f-953a-b0bf7f59f75d
DOI: 10.21203/rs.3.rs-1240394/v1

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Dexmedetomidine Alleviates Inflammatory Response and Oxidative Stress Injury of Vascular Smooth Muscle Cell via α2AR/PI3K/AKT Pathway in Intracranial AneurysmDOI 10.21203/rs.3.rs-1240394/v1Read

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