Article

Outcomes of Broader Genomic Profiling in Metastatic Colorectal Cancer: a Portuguese Cohort Study

2024-12-27

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC) is the third most diagnosed cancer globally and the second leading cause of cancer-related deaths. Despite advancements, metastatic CRC (mCRC) has a five-year survival rate below 20%. Next-generation sequencing (NGS) is recommended nowadays to guide mCRC treatment, however its clinical utility when compared with traditional molecular testing in mCRC is debated due to l...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7409632-95a9-5e02-a38b-7a304138e252
DOI: 10.20944/preprints202412.1295.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Outcomes of Broader Genomic Profiling in Metastatic Colorectal Cancer: a Portuguese Cohort StudyDOI 10.20944/preprints202412.1295.v2Read

Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.Semantic proximity Read

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.Semantic proximity Read

Molecular characterization of colorectal cancer (CRC) using next generation sequencing (NGS) in bridging the gap between research and clinical practice: from biomarker discovery to clinical implementationSemantic proximity Read

Molecular Profiling in Metastatic Colorectal Cancer.Semantic proximity Read

The Role of Multigene Panel Next-Generation Sequencing Techniques in Managing Patients with Metastatic Colorectal CarcinomaSemantic proximity Read

Genomic landscape of treatment refractory metastatic colorectal cancer.Semantic proximity Read

Multigene Panel Next-Generation Sequencing Techniques in the Management of Patients with Metastatic Colorectal Carcinoma: The Way Forward for Personalized Treatment? A Single-Center Experience.Semantic proximity Read

Next-Generation Sequencing in Colorectal Cancer: Real-World Molecular Profiling and Clinical Correlations.Semantic proximity Read

Real-World Molecular Testing in European Early-Onset Colorectal Cancer.Semantic proximity Read

Clinical utility of comprehensive genomic profiling test for colorectal cancer: A single institution prospective observational studySemantic proximity Read

Multigene panel next generation sequencing in metastatic colorectal cancer in an Australian population.Semantic proximity Read

Clinical Application of Targeted Deep Sequencing in Metastatic Colorectal Cancer Patients: Actionable Genomic Alteration in K-MASTER ProjectSemantic proximity Read