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Article

Multigene panel next generation sequencing in metastatic colorectal cancer in an Australian population.

PloS one - 1 Jan 2023

Nindra Udit, Pal Abhijit, Lea Vivienne, Lim Stephanie Hui-Su, Wilkinson Kate, Asghari Ray, Roberts Tara L, Becker Therese M, Farzin Mahtab, Rutland Tristan, Lee Mark, MacKenzie Scott, Ng Weng, Wang Bin, Lee C Soon, Chua Wei

Abstract excerpt

BACKGROUND: Next generation sequencing (NGS) is increasingly used in standard clinical practice to identify patients with potentially actionable mutations. Stratification of NGS mutation tiers is currently based on the European Society of Medical Oncology (ESMO) Scale for Clinical Actionability of Molecular Targets (ESCAT[E]) Tier I-V & X. Allele frequency is also increasingly recognised as an important...

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PMID: 37796807
DOI: 10.1371/journal.pone.0292087
PMCID: PMC10553362

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