Article

Regulatory Sharing Between Estrogen Receptor α Bound Enhancers

2020-03-20

Abstract excerpt

The human genome encodes an order of magnitude more gene expression enhancers than promoters, suggesting that most genes are regulated by the combined action of multiple enhancers. We have previously shown that neighboring estrogen-responsive enhancers, which are approximately 5,000 basepairs apart, exhibit complex synergistic contributions to the production of an estrogenic transcriptional response. Here we sough...

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Literature Corpus work: d710ccc7-c050-58f7-ab4e-bb3b92b64e19
DOI: 10.1101/2020.03.18.997403

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