Article

An RNA seq-based reference landscape of human normal and neoplastic brain

2023-01-03

Abstract excerpt

<h4>ABSTRACT</h4> In order to better understand the relationship between normal and neoplastic brain, we combined five publicly available large-scale datasets, correcting for batch effects and applying Uniform Manifold Approximation and Projection (UMAP) to RNA-seq data. We assembled a reference Brain-UMAP including 702 adult gliomas, 802 pediatric tumors and 1409 healthy normal brain samples, which can be utiliz...

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Literature Corpus work: 8f96e9b3-59f4-50e8-82bd-c2425e6ef863
DOI: 10.1101/2023.01.03.522658

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