Article

TopicNet: a framework for measuring transcriptional regulatory network change

2019-12-02

Abstract excerpt

<h4>Summary</h4> Next generation sequencing data highlights comprehensive and dynamic changes in the human gene regulatory network. Moreover, changes in regulatory network connectivity (network “rewiring”) manifest different regulatory programs in multiple cellular states. However, due to the dense and noisy nature of the connectivity in regulatory networks, directly comparing the gains and losses of targets of k...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6df0890-864c-568c-9402-a6d25a5dc01e
DOI: 10.1101/862177

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TopicNet: a framework for measuring transcriptional regulatory network changeDOI 10.1101/862177Read

CENTRA: Knowledge-Based Gene Contexuality Graphs Reveal Functional Master Regulators by Centrality and FractalitySemantic proximity Read

Modular Combinatorial Binding among Human <i>Trans</i> -acting Factors Reveals Direct and Indirect Factor BindingSemantic proximity Read

Identification of interpretable clusters and associated signatures in breast cancer single cell data: a topic modeling approachSemantic proximity Read

GenHITS: A network science approach to driver gene detection in human regulatory network using gene's influence evaluation.Semantic proximity Read

DiNeR: a <i>Di</i> fferential Graphical Model for analysis of co-regulation <i>Ne</i> twork <i>R</i> ewiringSemantic proximity Read

FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications.Semantic proximity Read

FUN-LDA: A LATENT DIRICHLET ALLOCATION MODEL FOR PREDICTING TISSUE-SPECIFIC FUNCTIONAL EFFECTS OF NONCODING VARIATIONSemantic proximity Read

Identification of candidate master transcription factors within enhancer-centric transcriptional regulatory networksSemantic proximity Read

A topic modelling analysis of TCGA breast and lung cancer transcriptomic dataSemantic proximity Read

Exploring the latent space of transcriptomic data with topic modelingSemantic proximity Read

Topic Modeling analysis of the Allen Human Brain AtlasSemantic proximity Read

Dynamic Network Analysis of the 4D NucleomeSemantic proximity Read