Article

DiNeR: a <i>Di</i> fferential Graphical Model for analysis of co-regulation <i>Ne</i> twork <i>R</i> ewiring

2020-05-30

Abstract excerpt

<h4>Background</h4> During transcription, numerous transcription factors (TFs) bind to targets in a highly coordinated manner to control the gene expression. Alterations in groups of TF-binding profiles (i.e. “co-binding changes”) can affect the co-regulating associations between TFs (i.e. “rewiring the co-regulator network”). This, in turn, can potentially drive downstream expression changes, phenotypic variatio...

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Literature Corpus work: 3aad4d30-0a67-5746-bafe-cc89fd8ba406
DOI: 10.1101/2020.05.29.124164

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