Article

CENTRA: Knowledge-Based Gene Contexuality Graphs Reveal Functional Master Regulators by Centrality and Fractality

2025-07-04

Abstract excerpt

Deciphering gene function via context-aware approaches is limited by various means. Especially static gene sets used in enrichment analyses and the lack of single-gene resolution in such analyses restrains the flexible association of genes with specific context. Here, we introduce CENTRA (Centrality-based Exploration of Network Topologies from Regulatory Assemblies), a framework that models gene contextuality thro...

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Literature Corpus work: 08fa5ee1-463f-5d42-bf2f-3b3228551607
DOI: 10.1101/2025.06.30.662180

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