Article

Identification of candidate master transcription factors within enhancer-centric transcriptional regulatory networks

2018-06-12

Abstract excerpt

Regulation of gene expression through binding of transcription factors (TFs) to cis-regulatory elements is highly complex in mammalian cells. Genome-wide measurement technologies provide new means to understand this regulation, and models of TF regulatory networks have been built with the goal of identifying critical factors. Here, we report a network model of transcriptional regulation between TFs constructed by...

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Literature Corpus work: a2a4eb5d-3c2c-58ae-940e-243b50729488
DOI: 10.1101/345413

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