Article

Mitochondrial fitness influences neuronal excitability of dopaminergic neurons from patients with idiopathic form of Parkinson’s disease

2023-04-28

Abstract excerpt

Parkinson disease is the second most common neurodegenerative disease defined by presence of Lewy bodies and the loss of dopaminergic neurons in the substantia nigra pars compacta (SNc). There are three types of PD - familial, early-onset and idiopathic. Idiopathic PD (IPD) accounts for approximately 90% of all PD cases. Mitochondrial dysfunction accompanies the pathogenesis of Parkinson’s disease. Loss of mitocho...

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Literature Corpus work: d6bdd9f9-139b-5ee8-9e39-00ac512c3010
DOI: 10.1101/2023.04.28.538698

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