Article
Emerging (and converging) pathways in Parkinson's disease: keeping mitochondrial wellness.
Biochemical and biophysical research communications - 19 Feb 2017
Cieri Domenico, Brini Marisa, Calì Tito
Abstract excerpt
The selective cell loss in the ventral component of the substantia nigra pars compacta and the presence of alpha-synuclein (α-syn)-rich intraneuronal inclusions called Lewy bodies are the pathological hallmarks of Parkinson's disease (PD), the most common motor system disorder whose aetiology remains largely elusive. Although most cases of PD are idiopathic, there are rare familial forms of the disease that can...
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