Article

EnrichSci: Transcript-guided Targeted Cell Enrichment for Scalable Single-Cell RNA Sequencing

2025-05-08

Abstract excerpt

Large-scale single-cell atlas efforts have revealed many aging-or disease-associated cell types, yet these populations are often underrepresented in heterogeneous tissues, limiting detailed molecular and dynamic analyses. To address this, we developed EnrichSci—a highly scalable, microfluidics-free platform that combines Hybridization Chain Reaction RNA FISH with combinatorial indexing to profile single -nucleus t...

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Literature Corpus work: 1ff1c897-a0fa-53b7-9869-e16ac1289efe
DOI: 10.1101/2025.05.02.651937

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