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Article

Spatial ciliary signaling regulates the dorsal/ventral regionalization of human brain organoids

2024-07-20

Abstract excerpt

Regionalization of the brain is a fundamental question in human developmental biology. Primary cilia are known for a critical organelle for dorsal/ventral fate of brain formation in mice, but little is known about how signaling in the primary cilia regulate regionalization of the human brain. Here, we found that signaling in the primary cilia function in regionalization of the brain using brain organoids derived f...

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Literature Corpus work
d67873cb-a452-5409-8674-1f50a83a5caa
DOI
10.1101/2024.07.18.604098
Open publication

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Spatial ciliary signaling regulates the dorsal/ventral regionalization of human brain organoidsDOI 10.1101/2024.07.18.604098
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