Article

A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

2021-08-09

Abstract excerpt

<h4>SUMMARY</h4> The phenotype of a cell and its underlying molecular state is strongly influenced by extracellular signals, including growth factors, hormones, and extracellular matrix. While these signals are normally tightly controlled, their dysregulation leads to phenotypic and molecular states associated with diverse diseases. To develop a detailed understanding of the linkage between molecular and phenotyp...

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Literature Corpus work: d66ff05f-5ae0-53c7-a4f1-364c81cb5635
DOI: 10.1101/2021.08.06.455429

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