Article

Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

2020-09-02

Abstract excerpt

Human oral soft tissues provide the first barrier of defence against chronic inflammatory disease and hold a remarkable scarless wounding phenotype. Tissue homeostasis requires coordinated actions of epithelial, mesenchymal and immune cells. However, the extent of heterogeneity within the human oral mucosa and how tissue cell types are affected during the course of disease progression is unknown. Using single cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a0e8f799-a73a-5ece-b780-c258f95ee6bf
DOI: 10.1101/2020.09.02.279406

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory diseaseDOI 10.1101/2020.09.02.279406Read

Mapping the Spatial Dynamics of the Human Oral Mucosa in Chronic Inflammatory DiseaseSemantic proximity Read

Single-cell atlas of human oral mucosa reveals a stromal-neutrophil axis regulating tissue immunity in health and inflammatory diseaseSemantic proximity Read

Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity.Semantic proximity Read

The Immunoregulatory Architecture of the Adult Oral CavitySemantic proximity Read

Single-cell RNA sequencing identifies heterogeneous cell subtypes within gingival tissueSemantic proximity Read

Integrative analysis of spatiotemporal transcriptomics delineates dynamic cell states in squamous tumorigenesisSemantic proximity Read

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerSemantic proximity Read

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerSemantic proximity Read

Single-Cell Transcriptome Atlas of the Canine Peri-implantitis Reveals stromal–immune cells interactionSemantic proximity Read

A Roadmap for the Human Oral and Craniofacial Cell AtlasSemantic proximity Read

Single-cell Transcriptional Analysis of the Cellular Immune Response in the Oral Mucosa of MiceSemantic proximity Read

Mapping Connective Tissue Molecular Blueprints to Illuminate Human Keratinized and Non-Keratinized Oral MucosaSemantic proximity Read