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Oncostatin M orchestrates collective epithelial migration via HIF1A activation

2025-09-27

Abstract excerpt

Extracellular signals strongly influence cell behavior, yet the mechanisms by which specific ligands mediate changes in phenotype remain unclear. The cytokine Oncostatin M (OSM) regulates homeostasis, wound healing, inflammation, and cancer progression. We previously found that OSM induces collective cell migration (CCM), a process where cells move as cohesive units while retaining cell-cell contacts, in MCF10A ma...

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Literature Corpus work
ba0cc916-1e73-5506-9221-89116688cd38
DOI
10.1101/2025.09.26.678830
Open publication

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Oncostatin M orchestrates collective epithelial migration via HIF1A activationDOI 10.1101/2025.09.26.678830
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