Article

Lignature: A Comprehensive Database of Ligand Signatures to Predict Cell-Cell Communication

2025-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Ligand-receptor interactions mediate intercellular communication, inducing transcriptional changes that regulate physiological and pathological processes. Ligand-induced transcriptomic signatures can be used to predict active ligands; however, the absence of a comprehensive set of ligand-response signatures has limited their practical application in predicting ligand-receptor interactions. To br...

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Literature Corpus work: dc57bb42-d8df-53fb-a7a4-5b3f0cf0fb7c
DOI: 10.1101/2025.03.22.644770

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