Article

Exploration of the circulating human secretome through protein quantitative trait analysis identifies an association between circulating levels of apolipoprotein L1 and risk of giant cell arteritis

2024-01-21

Abstract excerpt

<h4>Background</h4> Glucocorticoid monotherapy remains the principal treatment for giant cell arteritis (GCA), yet concurrent toxicity and adverse effects highlight the need for targeted therapies and improved risk stratification. Previous work suggests that evidence of genetic association can improve success rates in clinical trials and identify biomarkers for risk assessment, particularly when combined with othe...

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Literature Corpus work: d64e66c5-fd06-5795-b94d-09949a0b3683
DOI: 10.1101/2024.01.19.24301534

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Exploration of the circulating human secretome through protein quantitative trait analysis identifies an association between circulating levels of apolipoprotein L1 and risk of giant cell arteritisDOI 10.1101/2024.01.19.24301534Read

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