Article

ATHENA: A deep learning–based AI for functional prediction of genomic mutations and synergistic vulnerabilities in prostate cancer

2025-11-29

Abstract excerpt

Identifying functional mutations that drive therapy resistance remains a major challenge in prostate cancer. Large-scale sequencing often produces extensive lists of mutations but provides limited insight into which alterations are functionally relevant. To overcome this gap, we developed ATHENA (Attention-based Therapeutic Network Analyzer), a deep learning–based AI framework that predicts the functional impact...

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Literature Corpus work: d64c35a7-cf91-5960-b313-0028c1897d88
DOI: 10.1101/2025.11.26.690813

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