Article

Biologically informed deep neural network for prostate cancer classification and discovery

2020-12-09

Abstract excerpt

Determination of molecular features that mediate clinically aggressive phenotypes in prostate cancer (PrCa) remains a major biological and clinical challenge. Here, we developed a biologically informed deep learning model (P-NET) to stratify PrCa patients by treatment resistance state and evaluate molecular drivers of treatment resistance for therapeutic targeting through complete model interpretability. Using a m...

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Literature Corpus work: ca970780-baf9-5d80-8bbb-3b01472be024
DOI: 10.1101/2020.12.08.416446

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