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Article

Circular RNAs as Targets for Developing Anticancer Therapeutics

18 Jul 2025

Abstract excerpt

Circular RNA (CircRNA) is a single-stranded RNA arising from back splicing. CircRNAs interact with mRNA, miRNA, and proteins. These interactions regulate various life processes, including transcription, translation, cancer progression, anticancer drug resistance, and metabolism. Due to a lack of cap and poly(A) tails, circRNAs show exceptional stability and resistance to RNase degradation. CircRNAs exhibit...

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PMID: 40710359
DOI: 10.3390/cells14141106

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