Article

RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures

2022-01-17

Abstract excerpt

The exponential increase in the discovery and characterization of RNA tertiary structures has highlighted their active role in a variety of human disease, yet often their interactome and specific function remain unknown. Small molecules offer opportunities to both decode these cellular roles and develop therapeutics, yet there are few examples of small molecules that target biologically relevant RNA tertiary struc...

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Literature Corpus work: d5e37b64-d517-52bf-a9df-232a431fdf38
DOI: 10.1101/2022.01.16.476525

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