Article

Transcriptomic diversity of cell types across the adult human brain

2022-10-14

Abstract excerpt

The human brain directs a wide range of complex behaviors ranging from fine motor skills to abstract intelligence and emotion. However, the diversity of cell types that support these skills has not been fully described. Here we used high-throughput single-nucleus RNA sequencing to systematically survey cells across the entire adult human brain in three postmortem donors. We sampled over three million nuclei from a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 900a20e1-b5dc-51eb-8317-b11485a6005a
DOI: 10.1101/2022.10.12.511898

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic diversity of cell types across the adult human brainDOI 10.1101/2022.10.12.511898Read

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brainsSemantic proximity Read

Conserved cell types with divergent features between human and mouse cortexSemantic proximity Read

Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community OrganizationSemantic proximity Read

Comparative analysis of human brain organoids of brainstem and midbrain at single-cell resolutionSemantic proximity Read

Comprehensive cell atlas of the first-trimester developing human brainSemantic proximity Read

Transcriptomic cytoarchitecture reveals principles of human neocortex organizationSemantic proximity Read

Comparative transcriptomics reveals human-specific cortical featuresSemantic proximity Read

A single cell transcriptomic analysis of human neocortical developmentSemantic proximity Read

Mesoscale molecular architecture of the human striatum across cell types and lifespanSemantic proximity Read

A conserved cell-type gradient across the human mediodorsal and paraventricular thalamusSemantic proximity Read

Integrative single-cell analysis by transcriptional and epigenetic states in human adult brainSemantic proximity Read

PEDIA-BRAIN: A single nuclei multiomic encyclopedia of the human pons provides a resource for normal development and disease vulnerabilitySemantic proximity Read