Article

Microtubules deform the nucleus and force chromatin reorganization during early differentiation of human hematopoietic stem cells

2019-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Hematopoietic stem cells (HSC) can differentiate into all hematopoietic lineages to support hematopoiesis. Cells from the myeloid and lymphoid lineages fulfill distinct functions with specific shapes and intra-cellular architectures. The role of cytokines in the regulation of HSC differentiation has been intensively studied but our understanding of the potential contribution of inner cell archit...

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Literature Corpus work: d57c086e-29f4-55dc-a942-656896bb774b
DOI: 10.1101/763326

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