Article
Metabolically Active but Dysfunctional: The Role of Senescence and SASP in Metabolic Diseases
2025-07-18
Abstract excerpt
As we age or become overweight, certain cells in our bodies stop dividing and enter a state called “senescence.” Although these senescent cells no longer grow, they remain active and release a mix of inflammatory signals (known as SASP) that can harm nearby tissues. In fat, liver, and other organs, this ongoing inflammation makes it harder for cells to use insulin properly, leading to conditions like type 2 diabet...
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Identifiers and source
- Literature Corpus work
- d5547323-dab3-5725-9795-f9ffcceafa65
- DOI
- 10.20944/preprints202507.1550.v1