Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular senescence: Implications for metabolic disease.

Molecular and cellular endocrinology - 5 Nov 2017

Schafer Marissa J, Miller Jordan D, LeBrasseur Nathan K

Abstract excerpt

The growing burden of obesity- and aging-related diseases has hastened the search for governing biological processes. Cellular senescence is a stress-induced state of stable growth arrest strongly associated with aging that is aberrantly activated by obesity. The transition of a cell to a senescent state is demarcated by an array of phenotypic markers, and leveraging their context-dependent presentation is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Cell Death
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dasatinib

Share to Metabolic Diseases

Share to Myocardium

Share to Pancreas

Share to Quercetin

Source

Open in PubMed Open full text

Identifiers

PMID: 27591120
DOI: 10.1016/j.mce.2016.08.047
PMCID: PMC5857952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular senescence: Implications for metabolic disease.PMID 27591120Read ↗

Metabolically Active but Dysfunctional: The Role of Senescence and SASP in Metabolic DiseasesSemantic proximity Read ↗

Fat tissue, aging, and cellular senescenceSemantic proximity Read ↗

Ageing, cellular senescence and the impact of diet: an overviewSemantic proximity Read ↗

Role of Cellular Senescence in Type II Diabetes.Semantic proximity Read ↗

The interplay between obesity, immunosenescence, and insulin resistanceSemantic proximity Read ↗

Cellular senescence: at the nexus between ageing and diabetesSemantic proximity Read ↗

Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases.Semantic proximity Read ↗

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapiesSemantic proximity Read ↗

Cellular Senescence in Ageing, Age-Related Disease and LongevitySemantic proximity Read ↗

Senescent cells at the crossroads of aging, disease, and tissue homeostasisSemantic proximity Read ↗

Mechanisms and metabolic consequences of adipocyte progenitor replicative senescenceSemantic proximity Read ↗

Senescence and aging: Causes, consequences, and therapeutic avenuesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.