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Fat tissue, aging, and cellular senescence

5 Aug 2010

Abstract excerpt

Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in longevity and age-related metabolic dysfunction. Fat distribution and function change dramatically throughout life. Obesity is associated with accelerated onset of diseases common in old age, while fat ablation and certain mutations affecting fat increase life span. Fat cells turn over throughout the life span. Fat cell...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 20701600
DOI: 10.1111/j.1474-9726.2010.00608.x

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