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Article

The role of insulin receptors and IGF-I receptors in cancer and other diseases

1 Jan 2008

Abstract excerpt

There is evidence, both in vitro and in vivo, that receptor tyrosine kinases play a key role in the formation and progression of human cancer. In particular, the insulin-like growth factor receptor (IGF-IR), a tyrosine kinase receptor for IGF-I and IGF-II, has been well documented in cell culture, animal studies, and humans to play a role in malignant transformation, progression, protection from apoptosis, and...

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Share to Growth Hormone and Insulin-like Growth Factors
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Identifiers

PMID: 18465356
DOI: 10.1080/13813450801969715

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