Article
Circulating Tumor DNA Profiling for Detection, Risk Stratification, and Classification of Brain Lymphomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Mar 2023
Mutter Jurik A, Alig Stefan K, Esfahani Mohammad S, Lauer Eliza M, Mitschke Jan, Kurtz David M, Kühn Julia, Bleul Sabine, Olsen Mari, Liu Chih Long, Jin Michael C, Macaulay Charles W, Neidert Nicolas, Volk Timo, Eisenblaetter Michel, Rauer Sebastian, Heiland Dieter H, Finke Jürgen, Duyster Justus, Wehrle Julius, Prinz Marco, Illerhaus Gerald, Reinacher Peter C, Schorb Elisabeth, Diehn Maximilian, Alizadeh Ash A, Scherer Florian
Abstract excerpt
PURPOSE: Clinical outcomes of patients with CNS lymphomas (CNSLs) are remarkably heterogeneous, yet identification of patients at high risk for treatment failure is challenging. Furthermore, CNSL diagnosis often remains unconfirmed because of contraindications for invasive stereotactic biopsies. Therefore, improved biomarkers are needed to better stratify patients into risk groups, predict treatment response, and...
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