Analysis of Cellular Heterogeneity in Immune Microenvironment of Primary Central Nervous System Lymphoma by Single-Cell Sequencing

Abstract excerpt

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is characterized by a lack of specificity and poor prognosis. Further understanding of the tumor heterogeneity and molecular phenotype of PCNSL is of great significance for improving the diagnosis and treatment of this disease. METHODS: To explore the distinct phenotypic states of PCNSL, transcriptome-wide single-cell RNA sequencing was performed on...

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