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CSF-Seq enables transcriptome-wide profiling of cerebrospinal fluid and identifies prognostic signature of leptomeningeal disease

2026-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Leptomeningeal disease (LMD) is a rapidly fatal complication of systemic cancer for which sensitive diagnostic tools and informative biomarkers remain limited. Here, we introduce CSF-Seq, a method for whole-transcriptome sequencing of cell-free RNA (cfRNA) from human cerebrospinal fluid (CSF), designed to enable molecular profiling of LMD and other central nervous system (CNS) conditions. Using...

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Literature Corpus work
9c3ed16d-736f-581a-9bfc-b4359bbf23ff
DOI
10.64898/2026.05.21.725787
Open publication

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CSF-Seq enables transcriptome-wide profiling of cerebrospinal fluid and identifies prognostic signature of leptomeningeal diseaseDOI 10.64898/2026.05.21.725787
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