Article

Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma

2023-09-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The poor chemo-response and high DNA methylation of ovarian clear cell carcinoma (OCCC) have attracted extensive attentions. Recently, we revealed the mutational landscape of the human kinome and additional cancer-related genes and found deleterious mutations in <italic>ARID1A</italic>, a component of the SWI/SNF chromatin-remodeling complex, in 46% of OCCC pati...

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Literature Corpus work: d506287d-3e9b-5b87-bf88-2e282308851c
DOI: 10.21203/rs.3.rs-3354815/v1

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